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Duchenne muscular dystrophy is a serious condition caused by a recessive allele of a gene on the human X chromosome. The patients have muscles that weaken over time because they have absent or decreased dystrophin, a muscle protein. They rarely live past their 20s. How likely is it for a woman to have this condition?


A) Women can never have this condition.
B) One-half of the daughters of an affected man would have this condition.
C) One-fourth of the daughters of an affected father and a carrier mother could have this condition.
D) Very rarely: it is rare that an affected male would mate with a carrier female.
E) Only if a woman is XXX could she have this condition.

F) A) and D)
G) A) and C)

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When Thomas Hunt Morgan crossed his red-eyed F1 generation flies to each other, the F2 generation included both red- and white-eyed flies. Remarkably, all the white-eyed flies were male. What was the explanation for this result?


A) The gene involved is on the Y chromosome.
B) The gene involved is on the X chromosome.
C) The gene involved is on an autosome, but only in males.
D) Eye color in flies is a multifactorial trait.

E) B) and D)
F) B) and C)

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Please use the following information to answer the question(s) below. A plantlike organism on the planet Pandora can have three recessive genetic traits: bluish leaves, due to an allele (a) of gene A; a feathered stem, due to an allele (b) of gene B; and hollow roots due to an allele (c) of gene C. The three genes are linked and recombine. A geneticist did a testcross with an organism that had been found to be heterozygous for the three recessive traits and was able to identify progeny of the phenotypic distribution (+ = wild type) shown in Figure 12.3. Please use the following information to answer the question(s)  below. A plantlike organism on the planet Pandora can have three recessive genetic traits: bluish leaves, due to an allele (a)  of gene A; a feathered stem, due to an allele (b)  of gene B; and hollow roots due to an allele (c)  of gene C. The three genes are linked and recombine. A geneticist did a testcross with an organism that had been found to be heterozygous for the three recessive traits and was able to identify progeny of the phenotypic distribution (+ = wild type)  shown in Figure 12.3.   Figure 12.3 -In which progeny phenotypes has there been recombination between genes A and B? A)  1, 2, 5, and 6 B)  1, 3, 6, and 7 C)  2, 4, 5, and 8 D)  2, 3, 5, and 7 E)  in all 8 of them Figure 12.3 -In which progeny phenotypes has there been recombination between genes A and B?


A) 1, 2, 5, and 6
B) 1, 3, 6, and 7
C) 2, 4, 5, and 8
D) 2, 3, 5, and 7
E) in all 8 of them

F) D) and E)
G) A) and B)

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Which of the following is known as a Philadelphia chromosome?


A) a human chromosome 22 that has had a specific translocation
B) a human chromosome 9 that is found only in one type of cancer
C) an animal chromosome found primarily in the mid-Atlantic area of the United States
D) an imprinted chromosome that always comes from the mother

E) A) and C)
F) A) and B)

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Which of the following statements correctly describes linkage?


A) The closer two genes are on a chromosome, the lower the probability that a crossover will occur between them.
B) The observed frequency of recombination of two genes that are far apart from each other has a maximum value of 100%.
C) All of the traits that Mendel studied-seed color, pod shape, flower color, and others-are due to genes linked on the same chromosome.
D) Linked genes are found on different chromosomes.

E) All of the above
F) B) and C)

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In cats, black fur color is caused by an X-linked allele; the other allele at this locus causes orange color. The heterozygote is tortoiseshell. What kinds of offspring would you expect from the cross of a black female and an orange male?


A) tortoiseshell females; tortoiseshell males
B) black females; orange males
C) orange females; orange males
D) tortoiseshell females; black males
E) orange females; black males

F) A) and B)
G) B) and E)

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