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Refer to the graphs below, illustrating the free energy changes that occur during reactions in which glucose is oxidized to carbon dioxide and water. Refer to the graphs below, illustrating the free energy changes that occur during reactions in which glucose is oxidized to carbon dioxide and water.   Identify which graph corresponds to the laboratory oxidation of glucose and which corresponds to cellular oxidation of glucose.Explain how the overall free energy change compares in these two reactions and why.Also compare the form that the released energy takes in these two reactions. Identify which graph corresponds to the laboratory oxidation of glucose and which corresponds to cellular oxidation of glucose.Explain how the overall free energy change compares in these two reactions and why.Also compare the form that the released energy takes in these two reactions.

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Graph 1 represents glucose oxidation in ...

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Life in its earliest stages was very simple, and bacteria were the dominant life form.However, things changed about 2.3 billion years ago that allowed many new life forms to evolve and multicellularity to emerge.These changes were due to the rise in _______ levels in the atmosphere.

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Refer to the figure below. Refer to the figure below.   Some of the chemical energy present in pyruvate is harvested during an oxidation-reduction process taking place in the multistep reaction shown in the figure.In which molecule is this harvested chemical energy stored? A)  Pyruvate B)  NAD<sup>+</sup> C)  NADH D)  CO<sub>2</sub> E)  Coenzyme A Some of the chemical energy present in pyruvate is harvested during an oxidation-reduction process taking place in the multistep reaction shown in the figure.In which molecule is this harvested chemical energy stored?


A) Pyruvate
B) NAD+
C) NADH
D) CO2
E) Coenzyme A

F) B) and D)
G) A) and B)

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Atoms in triglycerides could be used in the synthesis of DNA.Which metabolic intermediate and pathway will function as crossover points between triglycerides and DNA?


A) Acetyl CoA and the citric acid cycle
B) Polysaccharides and glycolysis
C) Pyruvate and the citric acid cycle
D) Acetyl CoA and glycolysis
E) Amino acids and electron transport

F) A) and B)
G) A) and C)

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Oxidation and _______ always occur together.

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Which statement about the respiratory electron transport chain is true?


A) Electrons are received from NADH only.
B) Electrons are passed from donor to recipient carrier molecules in a series of oxidation-reduction reactions.
C) The terminal electron acceptor is usually H2O.
D) Most of the respiratory proteins are in the cytosol.
E) Energy must be added to move electrons from one electron carrier to the next.

F) A) and E)
G) None of the above

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During alcoholic fermentation, NAD+ is regenerated from NADH by the reduction of acetaldehyde to _______.

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Pyruvate oxidation generates


A) acetyl CoA and carbon dioxide.
B) lactic acid and NADH.
C) ethanol and carbon dioxide.
D) citrate and ATP.
E) amino acids and ATP.

F) B) and E)
G) A) and C)

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Refer to the table below. Refer to the table below.   The table summarizes the products (in moles)  of the complete oxidation of 1 mole of glucose and the complete oxidation of 1 mole of lauric acid, a fatty acid.Use this information to determine how energy production will compare when an equivalent amount of carbon dioxide is produced from oxidation events involving these two molecules. A)  The energy production will be equal for equal quantities of CO<sub>2</sub> production by these two molecules. B)  The energy production by lauric acid oxidation will be greater by 10 ATP when the two molecules are fully oxidized to produce equal quantities of CO<sub>2</sub>. C)  The energy production by glucose oxidation will be greater by 10 ATP when the two molecules are fully oxidized to produce equal quantities of CO<sub>2</sub>. D)  The energy production by lauric acid oxidation will be greater by 14 ATP when the two molecules are fully oxidized to produce equal quantities of CO<sub>2</sub>. E)  The energy production by glucose oxidation will be greater by 14 ATP when the two molecules are fully oxidized to produce equal quantities of CO<sub>2</sub>. The table summarizes the products (in moles) of the complete oxidation of 1 mole of glucose and the complete oxidation of 1 mole of lauric acid, a fatty acid.Use this information to determine how energy production will compare when an equivalent amount of carbon dioxide is produced from oxidation events involving these two molecules.


A) The energy production will be equal for equal quantities of CO2 production by these two molecules.
B) The energy production by lauric acid oxidation will be greater by 10 ATP when the two molecules are fully oxidized to produce equal quantities of CO2.
C) The energy production by glucose oxidation will be greater by 10 ATP when the two molecules are fully oxidized to produce equal quantities of CO2.
D) The energy production by lauric acid oxidation will be greater by 14 ATP when the two molecules are fully oxidized to produce equal quantities of CO2.
E) The energy production by glucose oxidation will be greater by 14 ATP when the two molecules are fully oxidized to produce equal quantities of CO2.

F) D) and E)
G) A) and E)

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Catabolic interconversion is a metabolic pathway in which


A) many small molecules are combined into larger molecules and a pathway that requires energy.
B) large molecules are built up into even larger molecules and a pathway that requires energy.
C) a large molecule is broken down into its constituent molecules and releases energy.
D) small molecules are broken down into CO2 and water molecules and release energy.
E) a citric acid intermediate is a starting point.

F) A) and C)
G) A) and E)

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Malate dehydrogenase is responsible for catalyzing which reaction?


A) Oxidation of malate to oxaloacetate
B) Reduction of malate to oxaloacetate
C) Oxidation of NADH to NAD+
D) Substrate phosphorylation of ADP to ATP
E) Decarboxylation of a five-carbon molecule to a four-carbon molecule

F) B) and E)
G) A) and C)

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Refer to the figure below. Refer to the figure below.   Of the compounds shown, which is the most oxidized, and which is the most reduced? A)  L is the most oxidized, and N is the most reduced. B)  N is the most oxidized, and O is the most reduced. C)  M is the most oxidized, and N is the most reduced. D)  O is the most oxidized, and M is the most reduced. E)  M is the most oxidized, and P is the most reduced. Of the compounds shown, which is the most oxidized, and which is the most reduced?


A) L is the most oxidized, and N is the most reduced.
B) N is the most oxidized, and O is the most reduced.
C) M is the most oxidized, and N is the most reduced.
D) O is the most oxidized, and M is the most reduced.
E) M is the most oxidized, and P is the most reduced.

F) B) and D)
G) A) and B)

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Refer to the table showing an accounting of ATP yield from different metabolic processes in a mouse cell.Yield is defined as the net number of molecules of ATP formed for every glucose molecule oxidized. Refer to the table showing an accounting of ATP yield from different metabolic processes in a mouse cell.Yield is defined as the net number of molecules of ATP formed for every glucose molecule oxidized.   Which statement explains why the two sets of values differ? A)  Some ATP is used in the beginning steps of glycolysis. B)  Glycolysis is a less efficient process than either pyruvate oxidation or the citric acid cycle. C)  Pyruvate oxidation and the citric acid cycle can only proceed when oxygen is present, whereas glycolysis is not dependent on oxygen. D)  NADH produced via glycolysis must be shuttled across the mitochondrial membrane through a process that converts each NADH to FADH<sub>2</sub>. E)  Because glycolysis is the first step in the overall oxidation of glucose, there is more opportunity for ATP to hydrolyze spontaneously in the cell before it can be used. Which statement explains why the two sets of values differ?


A) Some ATP is used in the beginning steps of glycolysis.
B) Glycolysis is a less efficient process than either pyruvate oxidation or the citric acid cycle.
C) Pyruvate oxidation and the citric acid cycle can only proceed when oxygen is present, whereas glycolysis is not dependent on oxygen.
D) NADH produced via glycolysis must be shuttled across the mitochondrial membrane through a process that converts each NADH to FADH2.
E) Because glycolysis is the first step in the overall oxidation of glucose, there is more opportunity for ATP to hydrolyze spontaneously in the cell before it can be used.

F) D) and E)
G) A) and D)

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Absence of _______ would disrupt the citric acid cycle but not glycolysis.


A) ADP
B) NAD+
C) FAD
D) CO2
E) ATP

F) A) and B)
G) B) and E)

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Which component of the respiratory chain is a peripheral protein?


A) Complex I
B) Complex II
C) Complex III
D) Complex IV
E) Cytochrome c

F) A) and C)
G) A) and B)

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Refer to the figure below. Refer to the figure below.   This figure illustrates how two oxidation-reduction reactions are coupled with electrons moving from one compound through another via the coenzyme _______. This figure illustrates how two oxidation-reduction reactions are coupled with electrons moving from one compound through another via the coenzyme _______.

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How many moles of high-energy phosphates are generated in converting 1 mole of glucose to lactate?


A) 1
B) 2
C) 3
D) 4
E) 36

F) C) and E)
G) A) and B)

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Organisms regulate certain metabolic enzymes in cells in order to maintain


A) a high level of catabolism.
B) a balance between catabolism and anabolism.
C) a high level of anabolism.
D) the biggest difference between catabolism and anabolism.
E) a constant enzymatic rate.

F) B) and D)
G) A) and E)

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Oxygen is used by


A) glycolysis.
B) the citric acid cycle.
C) the respiratory electron transport chain.
D) substrate-level phosphorylation.
E) ATP synthase.

F) A) and E)
G) A) and D)

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Examine the figure below, then answer the questions that follow. a. Which is the oxidizing agent, and which is the reducing agent? b. At the end of the reaction, which compound is oxidized and which is reduced? c. If this figure represents the metabolism of glucose, which letter represents glucose? Which letter represents O2? Examine the figure below, then answer the questions that follow. a. Which is the oxidizing agent, and which is the reducing agent? b. At the end of the reaction, which compound is oxidized and which is reduced? c. If this figure represents the metabolism of glucose, which letter represents glucose? Which letter represents O<sub>2</sub>?

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a) The reducing agent is A and the oxidi...

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