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In the face of uncompensated respiratory acidosis, which of the following blood gas abnormalities would you expect to encounter? I.decreased pH II.increased HCO3- III.increased PCO2 IV.increased pH


A) I, II, and IV
B) I and III
C) III only
D) II, III, and IV

E) B) and C)
F) A) and B)

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Which buffer system has the greatest capacity?


A) bicarbonate
B) hemoglobin
C) phosphates
D) plasma proteins

E) B) and C)
F) All of the above

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Which of the following acts as the "first-line" or immediate defense against the accumulation of H+ ions?


A) blood buffer systems
B) GI tract
C) renal system
D) respiratory system

E) B) and C)
F) B) and D)

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What is the primary buffer system for fixed acids?


A) Cl-
B) HCO3-
C) phosphate
D) plasma proteins

E) A) and B)
F) A) and C)

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What is the sum of all blood buffers in 1 L of blood?


A) buffer base
B) base excess
C) standard bicarbonate
D) base deficit

E) A) and B)
F) A) and C)

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When does a state of alkalemia exist? I.The HCO3-/CO2 ratio exceeds 20:1 II.The blood pH exceeds 7.45. III.The blood PCO2 exceeds 54 mm Hg.


A) II and III
B) I, II, and III
C) III only
D) I and II

E) B) and D)
F) B) and C)

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A patient has a bicarbonate concentration of 36 mEq and a PCO2 of 60 mm Hg. What is the approximate pH?


A) 7.2
B) 7.3
C) 7.4
D) 7.5

E) A) and D)
F) A) and C)

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Which of the following systems is primarily responsible for the buffering of fixed acids?


A) ammonia
B) HCO3-
C) Hb
D) phosphates

E) A) and B)
F) None of the above

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[H+] can be determined by the use of which factors? I.HCO3- II.H2CO3 III.inorganic phosphorus IV.PaO2


A) I, II, and III
B) II and III
C) IV only
D) I and II

E) A) and D)
F) A) and C)

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A patient has a confirmed metabolic acidosis with a normal PCO2. What inference can you draw from these findings?


A) A ventilatory disorder must coexist.
B) Compensation for the acidosis has begun.
C) The patient is hyperventilating.
D) The values obtained must be in error.

E) A) and D)
F) B) and C)

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Causes of respiratory acidosis in patients with normal lungs include which of the following? I.neuromuscular disorders II.spinal cord trauma III.anesthesia IV.central nervous system depression


A) I, II, III, and IV
B) III
C) II, III, and IV
D) II and IV

E) B) and D)
F) A) and D)

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Of what use is the Henderson-Hasselbalch equation for a clinician?


A) It can guide therapeutic decision for critically ill patients.
B) It establishes the baseline values for buffer enhancement treatments.
C) Given H2CO3 and CO2 values, the pH can be computed.
D) It allows validation of the reported values on a blood gas report.

E) All of the above
F) B) and C)

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Based on the following ABG results, what is the most likely acid-base diagnosis? pH = 7.62, PCO2 = 32 mm Hg, HCO3- = 29 mEq/L


A) acute (uncompensated) metabolic alkalosis
B) combined metabolic and respiratory alkalosis
C) partially compensated metabolic alkalosis
D) partially compensated respiratory acidosis

E) A) and C)
F) A) and B)

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What affect does hyperventilation have on the closed buffer systems?


A) causes them to bind with more H+
B) causes them to release more H+
C) has no affect on them at all
D) increases the affinity of the closed buffer system

E) A) and B)
F) A) and D)

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What factor would limit the ability of the H2CO3/HCO3- buffer system to perform efficiently?


A) temperature rise of more than 3 ∘\circ C
B) inadequate amount of 2,3-DPG in the blood
C) increased production of nonvolatile acids
D) lungs failing to excrete adequate levels of CO2

E) A) and D)
F) C) and D)

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Based on the following ABG results, what is the most likely acid-base diagnosis? pH = 6.89, PCO2 = 24 mm Hg, HCO3- = 4.7 mEq/L


A) acute (uncompensated) metabolic acidosis
B) acute (uncompensated) respiratory acidosis
C) partially compensated metabolic acidosis
D) partially compensated respiratory acidosis

E) A) and B)
F) A) and C)

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A patient has an anion gap of 21 mEq/L. Based on this information, what can you conclude? I.There is an abnormal excess of unmeasured anions in the plasma. II.The patient probably has metabolic acidosis. III.The concentration of fixed acids is increased.


A) II and III
B) I and II
C) I and III
D) I, II, and III

E) All of the above
F) A) and C)

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