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Sam works in construction and stepped on a sharp nail.He can't remember the last time he had a tetanus shot.What type of immunity is the most important for him to receive?


A) Natural active immunity
B) Artificial passive immunity
C) Natural passive immunity
D) Artificial active immunity
E) None of the choices will help him.

F) A) and C)
G) D) and E)

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Cell surface markers involved in immune reactions


A) are the result of genetic expression.
B) function in recognition of self molecules.
C) receive and transmit chemical messages among other cells of the system.
D) aid in cellular development.
E) all of the choices are correct.

F) C) and D)
G) B) and E)

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Which process involves antibodies cross-linking cells or particles into large aggregates?


A) Neutralization
B) Opsonization
C) Complement fixation
D) Agglutination
E) Anamnestic response

F) C) and D)
G) B) and E)

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All of the following characterize the secondary response to an antigen except


A) a higher titer of antibody is produced than the primary response.
B) a longer persistence of antibody than with the primary response.
C) a quicker rate of antibody synthesis than the primary response.
D) it is mostly IgM antibodies that are produced.
E) it is also known as the anamnestic response.

F) B) and E)
G) A) and B)

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Acellular vaccines and subunit vaccines


A) contain modified bacterial exotoxin molecules.
B) are always genetically engineered.
C) contain select antigenic components of a pathogen rather than whole cells or viruses.
D) confer passive immunity.
E) All of the choices are correct.

F) B) and E)
G) C) and D)

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Reliable vaccines exist for all of the following diseases except


A) Malaria.
B) Botulism.
C) Cholera.
D) Yellow fever.
E) Rabies.

F) A) and D)
G) None of the above

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Which of the following conditions have been conclusively proven to be linked to childhood vaccinations?


A) Autism
B) Diabetes
C) Asthma
D) All of the choices are correct.
E) None of the choices are correct.

F) B) and C)
G) None of the above

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A disadvantage of using an attenuated live microbe in a vaccine is that it can conceivably mutate back to a virulent strain.

A) True
B) False

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Alloantigens are the basis for an individual's blood group and MHC profile.

A) True
B) False

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Superantigens are


A) body tissues that the immune system mistakes as foreign.
B) cell markers found in some member of a species but not in other members.
C) bacterial toxins that activate T cells at a 100 times greater rate than other antigens.
D) those that evoke allergic reactions.
E) None of the choices are correct.

F) A) and B)
G) A) and E)

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C

Gamma globulin can be given as immunotherapy to confer artificial passive immunity.

A) True
B) False

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Which process involves antibodies coating microorganisms in order to facilitate phagocytosis?


A) Neutralization
B) Opsonization
C) Complement fixation
D) Agglutination
E) Anamnestic response

F) B) and C)
G) C) and D)

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After secreting antibodies during an immune response, plasma cells then differentiate into memory cells.

A) True
B) False

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False

The most significant cells in graft rejection are


A) helper T cells.
B) suppressor T cells.
C) cytotoxic T cells.
D) B cells.
E) natural killer (NK) cells.

F) A) and B)
G) B) and E)

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In the secondary response to an antigen, the predominant antibody is


A) IgD.
B) IgE.
C) IgG.
D) IgM.
E) IgA.

F) A) and E)
G) A) and C)

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During presentation of APC-bound antigen, macrophages secrete the cytokine, _____, that activates T helper cells.

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Certain body sites contain sequestered molecules, called _____ that escaped assessment during development of immune tolerance and are mistaken as foreign.

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Which immunoglobulin class/es can fix complement?


A) IgM only
B) IgG only
C) IgD only
D) IgM and IgG
E) IgE and IgA

F) B) and D)
G) A) and D)

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D

The molecular fragment on an antigen molecule that a lymphocyte recognizes and responds to is called a/an


A) epitope.
B) hapten.
C) antigen binding site.
D) variable region.
E) None of the choices are correct.

F) A) and D)
G) B) and C)

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Helper T cells


A) secrete antibodies.
B) function in allergic reactions.
C) directly destroy target cells.
D) suppress immune reactions.
E) activate B cells and other T cells.

F) C) and D)
G) B) and D)

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