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DNA Polymerase I


A) removes primers.
B) adds bases to new DNA chain.
C) seals DNA gaps.
D) proofreads DNA chain.

E) All of the above
F) B) and C)

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The antiparallel arrangement within DNA molecules refers to


A) each base bonding at the 1' position of the sugar.
B) a purine always bonding to a pyrimidine.
C) one helix strand that runs from the 5' to 3' direction and the other strand runs from the 3' to 5' direction.
D) an original parent DNA strand and one newly synthesized DNA strand comprising a new DNA molecule.

E) A) and C)
F) C) and D)

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Gene regulation can involve a protein repressor that blocks _____ from initiating transcription.


A) DNA polymerase I
B) DNA polymerase III
C) RNA polymerase
D) mRNA
E) rRNA

F) A) and B)
G) A) and C)

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A frameshift is caused by ______ mutations.


A) missense and insertion
B) missense and nonsense
C) nonsense and deletion
D) deletion and insertion
E) insertion and nonsense

F) C) and D)
G) B) and C)

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Which of the following is incorrect about transfer RNA?


A) has a bottom hairpin loop with an anticodon
B) has an anticodon that is complementary to a codon
C) contains a binding site for an amino acid
D) the initiator tRNA that binds to the P site has the anticodon UAC
E) initiator tRNA in bacteria carries tryptophan

F) B) and C)
G) B) and D)

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The lactose repressor


A) is transcribed with the structural lac genes.
B) is activated by binding lactose.
C) is inactivated by binding lactose.
D) requires lactose for its transcription.

E) None of the above
F) A) and B)

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Eukaryotic chromosomes differ from prokaryotic chromosomes because only eukaryotes have


A) histone proteins.
B) chromosomes in a nucleus.
C) several to many chromosomes.
D) elongated,not circular,chromosomes.
E) All of the choices are correct.

F) C) and D)
G) B) and C)

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In bacteria,initiator tRNA carries formyl methionine.

A) True
B) False

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Lactose is a corepressor in the lac operon.

A) True
B) False

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A screening system called the _____ test is used for detecting chemicals with carcinogenic potential.


A) Koch
B) Ames
C) mutation
D) cancer
E) Iowa

F) A) and C)
G) C) and E)

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A mutation has occurred during DNA replication while the cell was preparing to divide.As a result of this,the codon ACU of mRNA has now become ACC.Interestingly,there is no change to the protein being made.Why not?


A) This is a silent mutation.
B) The original amino acid isoleucine was changed to leucine,but they are the same variation of amino acid so no change to the protein.
C) The mutation was fixed,and even though the codon is now ACC the correct amino acid is put into place for the normal protein.
D) This is not a mutation that causes a big change,so there is no change to the protein being made.

E) B) and C)
F) A) and B)

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In Griffith's experiments with Streptococcus pneumoniae,rough nonencapsulated Streptococci were converted into smooth encapsulated Streptococci in the presence of the heat-killed smooth encapsulated Streptococci.Which microbial process had Griffith identified?


A) transduction
B) conjugation
C) transformation
D) cloning

E) B) and D)
F) All of the above

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Structural genes code for


A) ribosomal RNA molecules.
B) transfer RNA molecules.
C) cellular proteins.
D) gene expression elements.

E) All of the above
F) B) and C)

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Introns have no detectable functions.

A) True
B) False

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Which of the following is not a type of bacterial DNA recombination?


A) transformation
B) conjugation
C) mitosis
D) transduction

E) A) and C)
F) None of the above

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DNA polymerase III


A) is needed for adding nucleotides during mRNA synthesis.
B) synthesizes new DNA only in the 5' to 3' direction.
C) cannot add nucleotides to the lagging strand.
D) synthesizes an RNA primer.

E) All of the above
F) C) and D)

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If a codon for alanine is GCA,then the anticodon is


A) GCA.
B) CGT.
C) ACG.
D) CGU.
E) UGC.

F) B) and E)
G) D) and E)

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A _____ is a specific segment of DNA that codes for the production of one functional product.


A) intron
B) exon
C) gene
D) operator
E) triplet

F) A) and D)
G) A) and C)

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What type of mutation alters the base but not the amino acid being coded for?


A) silent
B) back
C) point
D) nonsense
E) missense

F) B) and D)
G) B) and C)

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Microorganisms exhibit genomes contained on


A) chromosomes.
B) plasmids.
C) mitochondrial DNA.
D) chloroplast DNA.
E) All of the choices are correct depending on the type of microorganism observed.

F) B) and D)
G) A) and C)

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