Question 1

The core promoter in eukaryotes is usually composed of which two features?

Accepted Answer

A)  transcriptional start site and enhancer
B)  transcriptional start site and response elements
C)  transcriptional start site and TATA box
D)  enhancer and TATA box
E)  response elements and TATA boxF) D) and E)
G) A) and E)

Question 2

MicroRNAs (miRNAs)

Accepted Answer

A)  are long RNA molecules.
B)  silence the expression of specific mRNAs.
C)  silence the expression of any mRNA present in the cytoplasm.
D)  are cut by an enzyme called transcriptase.
E)  are found only in animals.F) B) and E)
G) D) and E) B

Question 3

Liver cells,mammary cells,and skin cells all contain the same genome;however,their respective proteomes vary drastically.This observation is best explained by what phenomenon?

Accepted Answer

A)  gene splicing
B)  cell division
C)  cell differentiation
D)  crossing over
E)  evolutionF) A) and D)
G) A) and C)

Question 4

When the lac repressor binds to the lac operator site,RNA polymerase is prevented from transcribing which genes?

Accepted Answer

A)  the galactosidase gene
B)  a regulatory gene
C)  the galactoside transacetylase gene
D)  the galactosidase and galactoside transacetylase genes
E)  the galactosidase gene and a regulatory geneF) A) and E)
G) D) and E)

Question 5

Genes organized into an operon are beneficial to certain bacteria because the operon allows for

Accepted Answer

A)  discrete regulation of each gene encoding proteins with common functions.
B)  coordinated regulation of a group of genes that encode proteins in a common pathway.
C)  discrete regulation of each gene that encodes proteins with different functions.
D)  coordinated regulation of a group of genes that encode proteins used in different pathways.
E)  coordinated regulation of all the proteins within the genomE.F) A) and C)
G) A) and E)

Question 6

Events that occur during transcriptional regulation in eukaryotes include

Accepted Answer

A)  DNA replication.
B)  mRNA translation.
C)  RNA processing and export from the nucleus.
D)  polypeptide synthesis.
E)  all of thesE.F) B) and C)
G) B) and D)

Question 7

The major difference in gene regulation between prokaryotes and eukaryotes is

Accepted Answer

A)  eukaryotic and prokaryotic genes are usually grouped for common functions.
B)  eukaryotic genes regulation requires fewer signals than prokaryotic gene regulation.
C)  eukaryotic gene regulation is more simplistic than prokaryotic gene regulation.
D)  eukaryotic genes are arranged individually,while prokaryotic genes are grouped into operons.
E)  eukaryotic gene regulation tends to require less coordination and integration than prokaryotic gene regulation.F) All of the above
G) A) and E)

Question 8

Loosely packed chromatin is said to be in an open conformation.

Accepted Answer

A) True 
 B)False

Question 9

Unmethylated CpG islands are correlated with inactive genes.

Accepted Answer

A) True 
 B)False

Question 10

Certain drugs use RNA interference as a mechanism of action.What molecule would the active compounds of these drugs be composed of?

Accepted Answer

A)  Carbohydrate
B)  Steroid
C)  Protein
D)  Nucleic acid
E)  Small ionF) B) and D)
G) C) and E)

Question 11

A eukaryotic gene that is regulated by three activator proteins is said to be under

Accepted Answer

A)  triplet regulation.
B)  individual control.
C)  self-regulation.
D)  combinatorial control.
E)  elastic control.F) A) and E)
G) A) and D)

Question 12

The lacP site within the lac operon is upstream of the genes that encode for lactose uptake and metabolism proteins.The lacP site is

Accepted Answer

A)  the lac promoter site.
B)  where RNA polymerase binds.
C)  the site where genes are transcribed that encode proteins for metabolizing lactose.
D)  the lac promoter site where RNA polymerase binds.
E)  the lac promoter site,where genes are transcribed that encode proteins for metabolizing lactosE.F) A) and B)
G) C) and E)

Question 13

Both eukaryotes and prokaryotes require a promoter region for gene transcription.

Accepted Answer

A) True 
 B)False

Question 14

a(n.________ operon is one whose transcription is decreased by effector molecules.

Accepted Answer

A)  activated
B)  repressible
C)  inducible
D)  coinducible
E)  compressibleF) C) and E)
G) A) and B)

Question 15

When cytosolic levels of iron increase,intracellular ferritin levels will

Accepted Answer

A)  decrease.
B)  not change.
C)  increase.
D)  fluctuate by increasing and decreasing in a random fashion.
E)  drop until iron levels increase further.F) A) and E)
G) B) and E) C

Question 16

Bacteria can regulate gene expression by controlling the rate at which mRNA is translated into protein.

Accepted Answer

A) True 
 B)False

Question 17

A cell's ability to control their level of gene expression is called

Accepted Answer

A)  gene transformation.
B)  gene regulation.
C)  gene splicing.
D)  gene addition.
E)  gene correction.F) B) and D)
G) A) and E)

Question 18

Eukaryotic DNA methylation occurs on which base?

Accepted Answer

A)  guanine
B)  cytosine
C)  thymine
D)  adenine
E)  thymine and adenineF) A) and C)
G) A) and D)

Question 19

DNA methylation

Accepted Answer

A)  increases transcription.
B)  inhibits transcription.
C)  increases crossover events.
D)  decreases crossover events.
E)  promotes post-translational modification of proteins.F) A) and E)
G) A) and C)

Question 20

Genes expressed at relatively constant levels in tissues regardless of variations in the animal's condition are called a

Accepted Answer

A)  transposable element.
B)  steady state gene.
C)  constitutive gene.
D)  recombinant gene.
E)  multifunctional genE.F) A) and D)
G) C) and D) C

Exam 11: Gene Regulation

The core promoter in eukaryotes is usually composed of which two features?

Correct AnswerverifiedShow Answer

MicroRNAs (miRNAs)

Correct AnswerverifiedB

Liver cells,mammary cells,and skin cells all contain the same genome;however,their respective proteomes vary drastically.This observation is best explained by what phenomenon?

Correct AnswerverifiedShow Answer

When the lac repressor binds to the lac operator site,RNA polymerase is prevented from transcribing which genes?

Correct AnswerverifiedShow Answer

Genes organized into an operon are beneficial to certain bacteria because the operon allows for

Correct AnswerverifiedShow Answer

Events that occur during transcriptional regulation in eukaryotes include

Correct AnswerverifiedShow Answer

The major difference in gene regulation between prokaryotes and eukaryotes is

Correct AnswerverifiedShow Answer

Loosely packed chromatin is said to be in an open conformation.

Correct AnswerverifiedShow Answer

Unmethylated CpG islands are correlated with inactive genes.

Correct AnswerverifiedShow Answer

Certain drugs use RNA interference as a mechanism of action.What molecule would the active compounds of these drugs be composed of?

Correct AnswerverifiedShow Answer

A eukaryotic gene that is regulated by three activator proteins is said to be under

Correct AnswerverifiedShow Answer

The lacP site within the lac operon is upstream of the genes that encode for lactose uptake and metabolism proteins.The lacP site is

Correct AnswerverifiedShow Answer

Both eukaryotes and prokaryotes require a promoter region for gene transcription.

Correct AnswerverifiedShow Answer

a(n.________ operon is one whose transcription is decreased by effector molecules.

Correct AnswerverifiedShow Answer

When cytosolic levels of iron increase,intracellular ferritin levels will

Correct AnswerverifiedC

Bacteria can regulate gene expression by controlling the rate at which mRNA is translated into protein.

Correct AnswerverifiedShow Answer

A cell's ability to control their level of gene expression is called

Correct AnswerverifiedShow Answer

Eukaryotic DNA methylation occurs on which base?

Correct AnswerverifiedShow Answer

DNA methylation

Correct AnswerverifiedShow Answer

Genes expressed at relatively constant levels in tissues regardless of variations in the animal's condition are called a

Correct AnswerverifiedC

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B

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C

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C