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In a woman's monthly cycle,the hormone _____ is released when estrogen reaches a peak.


A) luteinizing hormone
B) oxytocin
C) progesterone
D) testosterone
E) human chorionic gonadotrophin

F) C) and D)
G) C) and E)

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In women,blocked oviducts can result from sexually transmitted diseases.

A) True
B) False

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Explain the reasoning behind the laws in some European countries that limit the number of children that can result from a single sperm donor. Do you agree with these restrictions?  Why or why not?

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Answers will vary.
Background:
Some Euro...

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The first successful outcome of gene therapy was in a case of a young girl suffering from ____________________,who was supplied with normal copies of the ADA gene.

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SCID
sever...

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Fertilization takes place in the ____________________,and the embryo grows and develops in the ____________________.

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oviduct; u...

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Which scenario describes a situation for which genetic counseling is recommended?


A) Couples who have no family history of genetic disorders
B) Women under age 35 who plan to become pregnant
C) Couples who already have a child with a birth defect
D) Couples who have undergone IVF
E) Women who have had one miscarriage, and no other pregnancies

F) A) and E)
G) All of the above

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Intracytoplasmic sperm injection (ICSI) is used by couples in which the _____.


A) female has blocked oviducts
B) female has very irregular ovulation
C) female is approaching menopause
D) source of sperm is a sperm bank
E) male is infertile

F) D) and E)
G) None of the above

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The most common vectors used in DNA therapy experiments are _____.


A) modified human cells
B) retroviruses and adenoviruses
C) antisense oligonucleotides (AONs)
D) bacteria
E) naked DNA

F) A) and C)
G) A) and E)

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Approximately _____ percent of human births in the U.S.are the result of in vitro fertilization.


A) 0.5
B) 1.5
C) 5
D) 10
E) 25

F) A) and D)
G) B) and E)

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The risk of ____________________,which occurs when the embryo begins to grow outside the uterus,increases with the use of IVF.

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The most common cause of low sperm count in males is _____.


A) varicocele
B) undescended testicles
C) testicular failure
D) semen disorders
E) obstructions

F) C) and E)
G) C) and D)

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Consider an infertile couple,of which both partners are able to produce healthy gametes,but the woman's history of endometriosis has rendered her unable to carry a fetus. Suppose this couple undergoes IVF with their own gametes,followed by embryo transfer to the uterus of a gestational surrogate,and the birth of a baby. What is the genetic relationship between the surrogate and the baby?


A) The baby shares only X chromosomal DNA with the gestational surrogate.
B) The baby shares 25% of its genes with the gestational surrogate.
C) The baby shares half of its genes with the gestational surrogate.
D) The baby is genetically identical to the gestational surrogate.
E) There is no genetic relationship between the gestational surrogate and the baby.

F) B) and C)
G) A) and D)

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To treat severe combined immunodeficiency (SCID) by gene therapy,a patient's white blood cells are removed,followed by the delivery of a normal gene into the cells.The altered cells are then returned to the patient's body.This is an example of _____ gene therapy.


A) enhancement
B) germ-line
C) viral
D) in vivo
E) ex vivo

F) C) and D)
G) A) and B)

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The birth of Louise Brown was the first person born as a result of _____.


A) in vitro fertilization
B) sex selection
C) intrauterine insemination
D) laparoscopy
E) genetically engineering of human-animal hybrids

F) A) and D)
G) A) and C)

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What technique can be used to detect genetic defects in early stage embryos,prior to implantation?


A) genetic screening
B) chorionic villus sampling
C) PGD
D) amniocentesis
E) micromanipulation

F) A) and B)
G) A) and C)

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Usually,the first procedure a genetic counselor performs for a client is _____.


A) amniocentesis
B) construction of a karyotype
C) biochemical testing
D) construction of a pedigree based on family and medical histories
E) ultrasonic imaging

F) A) and E)
G) None of the above

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Discuss the reasons why ART leads to more multiple and premature births than the general population.

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Each year,about 1.5% of babies born in t...

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____________________ assess the risks of developing,inheriting,or transmitting genetic disorders,and assist clients in understanding this information.

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Amniocentesis poses increased risks to the fetus and mother.

A) True
B) False

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The technique of ____ is a form of genetic disorder therapy in which a patient's defective protein is artificially provided.


A) PGD
B) exon splicing
C) exon skipping
D) intron skipping
E) enzyme replacement therapy

F) A) and B)
G) A) and C)

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