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Which is the correct order of events during the inflammatory response?


A) Vasodilation,margination,diapedesis,phagocytosis
B) Phagocytosis,margination,diapedesis,vasodilation
C) Diapedesis,vasodilation,phagocytosis,margination
D) Margination,vasodilation,diapedesis,phagocytosis

E) None of the above
F) All of the above

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During phagocytosis,the phagolysosome forms before the phagosome forms.

A) True
B) False

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Substances that are recognized as foreign and provoke immune responses are called _________.


A) antibodies.
B) antigens.
C) infective agents.
D) inducers.

E) B) and D)
F) C) and D)

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The ________ is a large organ in the abdominal cavity that specializes in filtering the blood and trapping bloodborne microorganisms and antigens.

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Lactobacillus contributes to the antimicrobial defenses for the adult female reproductive tract by making lactic acid to lower the pH.

A) True
B) False

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How does the action of exocytosis by dendritic cells and macrophages differ from that of neutrophils?


A) Dendritic cells and macrophages primarily act as antigen-presenting cells,whereas neutrophils primarily release microbial fragments.
B) Dendritic cells and macrophages primarily release microbial fragments,whereas neutrophils primarily act as antigen-presenting cells.
C) Dendritic cells and macrophages primarily release products of autophagy,whereas neutrophils primarily release products of any cellular origin.
D) Dendritic cells and macrophages primarily release products of any cellular origin,whereas neutrophils primarily release products of autophagy.

E) None of the above
F) A) and D)

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Which of the following types of leukocytes is typically elevated in cases of bacterial,rather than viral or helminthic,infection?


A) Neutrophils
B) Basophils
C) Monocytes
D) Eosinophils

E) None of the above
F) B) and D)

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Which is the correct order of protein mediators that are produced during an acute inflammatory response?


A) Selectins,integrins,chemotaxins,kallikreins
B) Kallikreins,chemotaxins,integrins,selectins
C) Chemotaxins,selectins,kallikreins,integrins
D) Integrins,kallikreins,selectins,chemotaxins

E) A) and D)
F) A) and B)

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The lungs are protected from microorganisms by


A) the mucociliary blanket.
B) lysozyme in mucus.
C) phagocytic action of alveolar macrophages.
D) All of the choices are correct.

E) C) and D)
F) None of the above

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Eosinophils defend against protist and helminth parasites by


A) phagocytosis.
B) complement activation.
C) antibody production.
D) releasing cationic proteins and reactive oxygen metabolites.

E) C) and D)
F) B) and D)

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In birds,the __________ of Fabricius is where B cells undergo maturation.

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Why is innate host resistance a type of nonspecific immune response?


A) Innate resistance is nonspecific because any foreign material,microorganisms,or antigens encountered by the host are targeted.
B) Innate resistance is nonspecific because any type of immune response,such as inflammation,phagocytosis,or humoral immunity,is activated in the host by foreign material.
C) Innate resistance is nonspecific because it is impossible to determine the specific degree by which any host will respond when foreign material or microorganisms are present.
D) Innate resistance is nonspecific because it depends on the life experience of the individual,for example,receiving a vaccine or acquiring a disease due to a particular pathogen.

E) A) and B)
F) A) and C)

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Which of the following is a physical barrier in the nonspecific defense of a mammalian host?


A) Inflammation
B) Phagocytosis
C) Fever
D) Mucous membranes

E) C) and D)
F) B) and C)

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Which of the following is considered to be a biological defense mechanism?


A) Skin
B) Fever
C) Gastric acid
D) Normal microbiota

E) B) and D)
F) None of the above

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An intraepidermal lymphocyte migrates to a lymph node and matures into a dendritic cell after phagocytosis of an antigen.

A) True
B) False

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The inhalation of cigarette smoke and similar pollutants has a gradual effect on cilia lining the respiratory tract,first causing the beating to slow and eventually stop.How does this change in cilia most directly impact the resistance mechanisms of the host?


A) Innate host immunity due to mechanical barrier protection would be lost
B) Acquired immunity due to antibody response would be lost
C) Both acquired and nonspecific immunity would be lost
D) Neither acquired nor nonspecific immunity would be lost

E) B) and D)
F) All of the above

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Under normal circumstances,which of the following is(are) normally sterile environments in mammals?


A) Kidneys
B) Ureters
C) Urinary bladder
D) All of the choices are correct.

E) A) and B)
F) A) and C)

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Dendritic cells


A) play an important role in the development of allergies and hypersensitivity.
B) contain granules with histamine and other pharmacologically active substances that contribute to the inflammatory response.
C) are capable of recognizing specific pathogen-associated molecular patterns and play an important role in nonspecific resistance.
D) are mainly important in the defense against protozoan and helminth parasites.

E) B) and C)
F) B) and D)

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During phagocytosis,signs and symptoms of illness peak following phagolysosome formation if the pathogen is Gram-positive.

A) True
B) False

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Defensins act against bacteria and fungi by permeabilizing cell membranes.

A) True
B) False

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