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Human mtDNA is about 16,000 bp in size.

A) True
B) False

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In reciprocal crosses of animals, extranuclear inheritance typically results in the exclusive expression of the maternal phenotype.

A) True
B) False

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A horticulturist who has not taken genetics is collecting seeds from flowers produced on different branches of a variegated plant. He separates and packages the seeds produced from normal green portions of the plant, from variegated branches, and from pure white portions, and markets them as normal, variegated, and albino varieties, respectively. Which patrons are likely to be unhappy with their purchase?

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The purchasers of the albino variety, the white color of which means it is completely chlorophyll-deficient. These plants will die as seedlings as soon as the endosperm resources of the seed are exhausted.

As a conservation geneticist, you are interested in saving the genetic heritage of an endangered bird species that has dwindled in population size to just a few individuals. You decide the best course of action is to attempt to hybridize these individuals with a related species. There are several species that look similar to the endangered bird species, but some are likely to be more closely related to it than others. How might you use mtDNA to help select the hybrid partner for your captive breeding program, and why might it be important to select the closest relative?

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mtDNA sequences for several regions, inc...

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Some parasitic or symbiotic organisms are passed from parent to offspring transovarially-through the egg-by invading the egg cytoplasm. A general term for this phenomenon is


A) infectious heredity.
B) extrachromosomal inheritance.
C) Lamarckian heredity.
D) parasitic inheritance.
E) extranuclear inheritance.

F) B) and E)
G) All of the above

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Which of the following enzymes are required for mitochondrial function?


A) DNA polymerase
B) Aminoacyl synthetase
C) RNA polymerase
D) Cyclohexamide
E) Cytochrome oxidase

F) All of the above
G) A) and B)

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The Malagasy people, who are native to the island of Madagascar off the African coast, are linguistically and phenotypically more similar to Indonesians than they are to mainland Africans. Outline a test of relationship using mitochondrial DNA.

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As in the above questions, select portions of the mitochondrial genome can be sequenced (or haplotypes can be obtained with restriction enzymes) to obtain informative polymorphism data. Samples from all three regions (Africa, Madagascar, and Indonesia) can then be compared for similarities and differences and added to linguistic and other data.

The malarial protist Plasmodium, which is an obligate internal parasite of the blood of vertebrates, possesses a dysfunctional plastid. Formulate a hypothesis as to how this organism, which is never exposed to light, may have acquired its plastid. How could you test this hypothesis?

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Plasmodium could have inherited its plastid from a free-living photosynthetic protist ancestor. Alternatively, the plastid could have been secondarily acquired by symbiosis with a plastid-bearing organism (perhaps another protist). It is difficult to test these hypotheses, but any test would begin with plastid DNA sequence and a comparison with known sequences of bacteria and other plastids.

Pigmentless chloroplasts are called albinoplasts.

A) True
B) False

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Purple nonsulfur photosynthetic bacteria are the group of bacteria most closely related to modern mitochondria. Does this mean that mitochondria evolved from these bacteria?

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No, it suggests that modern mitochondria...

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In mitochondria, the initiator codon specifies F-met tRNA, as with nuclear genes.

A) True
B) False

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mRNAs transcribed in the mitochondria are translated in the


A) mitochondria.
B) cytoplasm.
C) nucleus.
D) All of the above
E) None of the above

F) C) and E)
G) A) and E)

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Which of the following statements is true?


A) Mitochondrial genomes of different organisms are about the same size.
B) Mitochondrial DNA is typically biparentally inherited.
C) Mitochondrial genomes are almost identical to chloroplast genomes.
D) Mitochondrial genes are similar to bacterial genes in structure.
E) Mitochondrial DNA is rarely supercoiled.

F) B) and E)
G) C) and D)

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In all plants, as in animals, extranuclear DNA is maternally inherited.

A) True
B) False

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Cells with more than one mitochondrial genotype are


A) heteroplasmic.
B) polymorphic.
C) heterozygous.
D) homoplasmic.
E) homozygous.

F) B) and D)
G) A) and C)

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Some proteins consist of a combination of mitochondrial-encoded and nuclear-encoded subunits.

A) True
B) False

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Certain sea turtles that feed along the coast of South America migrate hundreds of miles in open ocean back to their natal south Atlantic island beaches in order to breed. An intriguing hypothesis proposed by marine biologist Archie Carr in the 1980s suggested that turtles in these populations began this migration pattern millions of years ago when the continental coast was much closer to the islands. As the continents drifted, the turtles were forced to migrate farther and farther out to sea. Can you think of a way to use mtDNA to test this hypothesis?

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One prediction of the hypothesis is that...

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Explain how the inheritance of dextral vs. sinistral coiling in Limnaea snails is an example of maternal effect but not maternal inheritance.

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The shell-coiling trait is controlled by...

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The phenomenon where the expression of certain genes is determined by whether they are inherited from the maternal parent or paternal parent is called


A) maternal inheritance.
B) maternal effect.
C) extranuclear inheritance.
D) genetic imprinting.
E) uniparental inheritance.

F) A) and D)
G) B) and E)

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From the Chlamydomonas cross mt+ [eryr] × mt- [erys], most of the offspring


A) are erythromycin resistant.
B) whichever phenotype is shown by the female parent.
C) are mating type mt+.
D) are erythromycin sensitive.
E) whichever phenotype is shown by the male parent.

F) B) and E)
G) D) and E)

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