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Which of the following characteristics would NOT make a molecule more antigenic?


A) a molecule with many epitopes
B) a molecular mass less than 5000 daltons
C) a stable molecule that maintains a definite shape
D) a complex molecule with many antigenic determinants
E) complex molecules like a glycoprotein or phospholipid

F) All of the above
G) C) and D)

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IgM is the most common class of antibodies in the blood.

A) True
B) False

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Clonal deletion removes lymphocytes that react to .

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Which of the following statements about helper T cells is incorrect?


A) They can be distinguished from other T lymphocytes by the presence of certain glycoproteins.
B) They function in conjunction with B cells.
C) They secrete messenger proteins called perforins.
D) There are two types: TH1 and TH2.
E) They are destroyed in HIV- infected individuals.

F) All of the above
G) C) and E)

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Discuss the basic structure of the antibody molecule.

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The antibody molecule is composed of fou...

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Secretory IgA and the IgA in the blood have the same chemical composition.

A) True
B) False

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Cytokines are soluble regulatory proteins that act as intercellular signals and include substances such as interleukins, interferon, and growth factors.

A) True
B) False

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The MALT lacks the tough outer capsule of a lymph node, but functions in the same way.

A) True
B) False

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The immunological synapse refers to the


A) binding of a monocyte or macrophage to the antigen so that it can act as an antigen- presenting cell.
B) interaction of the many cytokines produced by different immunological cells.
C) interaction between a T cell and an antigen- presenting cell to produce a specialized contact area for communication between these cells.
D) interaction between lymphocytes and foreign antigens to produce memory cells.
E) activation of a B cell to become a plasma cell.

F) C) and D)
G) A) and C)

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Major histocompatibility antigens are


A) glycoproteins found on the surface of most vertebrate animals.
B) antigens that provoke allergic reactions.
C) antigens attached to foreign invaders.
D) not really antigens, but rather antibodies produced to mask foreign antigens.
E) antigens that must be processed by cells called histiocytes in order to be recognized by the immune system.

F) B) and E)
G) B) and D)

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When a T cell and an antigen- presenting cell interact, a specialized contact called a(n) _ forms between them.

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immunologi...

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All of the following are true of lymph EXCEPT:


A) It flows toward the heart.
B) It has no unique pump.
C) Lymphocytes and antibodies flow through the lymph.
D) It comes from fluid that has leaked out of blood vessels.
E) It contains wastes such as degraded proteins and toxins.

F) A) and B)
G) B) and E)

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Peyer's patches are found in the


A) mammary glands.
B) spleen.
C) tonsils.
D) small intestine.
E) respiratory tract.

F) B) and D)
G) A) and B)

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Which of the following is NOT considered a function of an antibody?


A) They can bind two microbial cells together, leading to agglutination.
B) They can enhance phagocytosis.
C) They can produce toxins that directly kill bacteria.
D) They can block the attachment molecules on the surface of bacteria and viruses in order to prevent them from attaching to their target cells.
E) They can bind to crucial parts of toxins and deactivate them.

F) C) and E)
G) B) and D)

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The type of immunoglobulin produced during the initial stages of an immune response is


A) IgD.
B) IgM.
C) IgE.
D) IgA.
E) IgG.

F) All of the above
G) None of the above

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Describe the mechanisms of action of antibodies.

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Antibodies act against foreign antigens ...

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Class II MHC (major histocompatibility) antigens are only found on


A) muscle.
B) red blood cells.
C) lymphocytes and antigen- presenting cells.
D) nucleated cell membranes.
E) the skin.

F) B) and C)
G) A) and E)

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Which of the following statements concerning T- independent responses is incorrect?


A) They are slow responses.
B) Cytokines are required for their success.
C) T- independent antigens produce extensive cross- linking between BCRs.
D) They can involve Toll- like receptors on B cells.
E) They are weak and disappear quickly.

F) All of the above
G) None of the above

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Enhanced immune responses to subsequent exposures to an antigen to which the body has already been exposed are known as


A) autoimmune responses.
B) primary immune responses.
C) allergic responses.
D) third- degree immune responses.
E) memory responses.

F) B) and D)
G) A) and B)

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The Fc portion of an antibody is formed by


A) the lower portions of the heavy chains.
B) one light chain and one heavy chain.
C) the upper portions of the light chains.
D) the upper portions of the heavy chains.
E) the lower portions of the light chains.

F) A) and C)
G) B) and C)

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