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In terms of evolution,what is the most significant outcome of translocation in a species' genome?


A) production of gene families
B) development of two species due to reproductive isolation
C) eventual extinction due to semisterility
D) Down syndrome
E) Klinefelter syndrome

F) B) and E)
G) C) and E)

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Explain how data from the linkage groups of the mouse can be used as a resource for assessing human linkage groups.

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Because virtually all genes cloned from ...

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Which of the following does not happen when an intragenic inversion occurs?


A) One part of the gene is relocated to a distant region of the chromosome.
B) One part of the gene stays at its original site.
C) One part of the gene is relocated to another chromosome.
D) The gene's function remains unaffected.
E) The length of the chromosome remains unaffected.

F) A) and C)
G) B) and E)

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An acentric fragment is an inversion crossover product lacking a centromere.

A) True
B) False

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Despite selection against chromosomal variations


A) related species almost always have the same karyotype.
B) total DNA content varies widely between individuals within the same species.
C) closely related species diverge by many chromosomal rearrangements.
D) distantly related species diverge by only a few chromosomal rearrangements.
E) related species almost always have a different karyotype.

F) A) and B)
G) A) and C)

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Turner syndrome,XO,is a sex chromosome aneuploidy.Of the effects listed below,which one is not usually seen in this syndrome?


A) unusually short stature
B) infertility
C) skeletal abnormalities
D) unusually long limbs
E) abnormal karyotype

F) A) and B)
G) B) and E)

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The genus Triticale is a new genus of the various allopolyploid hybrids between wheat and rye.Some of the members of this genus show agricultural promise because


A) wheat has a high yield.
B) rye adapts well to unfavorable environments.
C) wheat has a high level of protein.
D) rye has a high level of lysine.
E) All of the choices are correct.

F) C) and D)
G) None of the above

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We now know that several organisms have a high degree of synteny at the genomic level.You wish to test the hypothesis that the laboratory mouse and humans share genomic similarities.What tests would you complete and given that we now know that the mouse and human genomes are highly syntenic,what results would you expect?

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Karyotype analysis can be used to test t...

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Which of the following would be most difficult to identify by comparative genomic hybridization (CGH) ?


A) duplication
B) deletion
C) monosomy
D) base substitution
E) trisomy

F) C) and D)
G) D) and E)

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The various types of transposable elements have many things in common.Which of the following is not a usual characteristic of them?


A) larger than 50 kb
B) may be present in a genome from one to thousands of times
C) found only in a select group of organisms
D) need not be sequences that do something for the organism
E) can alter gene expression

F) C) and D)
G) B) and C)

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During the pairing of homologues in prophase of meiosis I,the region of a normal,nondeleted chromosome that has nothing with which to recombine forms a so-called


A) inversion loop.
B) deletion heterozygote.
C) crossover suppressor.
D) D loop.
E) deletion loop.

F) A) and B)
G) A) and E)

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What are the possible effects of transposable elements on gene function,and how do these relate to evolution?

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The insertion of a transposable element ...

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Of the following segregation patterns,which one is most likely to result in a normal zygote?


A) alternate
B) adjacent-1
C) adjacent-2
D) nondisjunction
E) triploid

F) C) and D)
G) All of the above

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Which of the following is most likely to produce a chromosomal inversion?


A) aneuploidy
B) one double-strand breakage on each of two different chromosomes
C) transposition of a retrotransposon
D) double-strand breakage at two positions on the same chromosomes
E) Robertsonian translocation

F) A) and B)
G) B) and D)

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Which of the following sex chromosome aneuploidies is not usually seen in live births?


A) XO
B) XXY
C) YO
D) XXX
E) None of the choices are correct.

F) B) and D)
G) A) and B)

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In Drosophila,a gynandromorph,which is composed of equal parts of male and female tissue,results from


A) an XX female losing one X chromosome during the first mitotic division after fertilization.
B) an egg carrying an X chromosome fertilized by a Y-carrying sperm.
C) a normal egg fertilized by both an X-carrying sperm and a Y-carrying sperm.
D) the fusion of a female embryo with a male embryo.
E) the fusion of a female egg by an XX sperm.

F) A) and B)
G) C) and E)

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Explain the differences between chromosomal rearrangements and changes in chromosome number.Cite at least one example of each.

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Chromosomal rearrangements reorganize th...

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A hallmark of transposons is that their ends are inverted repeats of each other.

A) True
B) False

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In general,which of the following usually has a greater chance of lethality than the others?


A) inversion
B) duplication
C) deletion
D) translocation
E) transcription

F) A) and B)
G) All of the above

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What are LINEs and SINEs?

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LINEs are long interspersed elements and...

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