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During the second stage of the inflammatory response, what do neutrophils accomplish when they migrate to areas of damaged tissue?


A) Neutrophils destroy bacteria and other cellular debris.
B) Neutrophils increase capillary permeability.
C) Neutrophils are potent vasodilators.
D) Neutrophils interfere with the ability of viruses or bacteria to infect other cells.

E) All of the above
F) C) and D)

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Self antigens usually generate an immune response in our own bodies.

A) True
B) False

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The lymph ducts in the thoracic cavity drain into the:


A) junction of the internal jugular vein and subclavian vein.
B) junction of the brachiocephalic vein and the superior vena cava.
C) inferior vena cava.
D) external jugular veins.

E) A) and B)
F) None of the above

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Which antibody is NOT secreted by B cells in significant amounts?


A) IgD
B) IgG
C) IgE
D) IgM

E) A) and B)
F) A) and C)

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Explain the role of major histocompatibility complex (MHC) molecules in T cell activation.

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T cell activation begins with a cell processing and displaying antigen fragments on its MHC molecules. It then presents the antigen to a particular T cell clone, which is specific for its individual MHC -antigen complex. When the T cell receptor recognizes and binds this complex, multiple changes are triggered inside the T cell and the process of activation begins. This process is known as clonal selection because the antigen "selects" a particular T cell clone. Full T cell activation requires the interaction of the T cell with other molecules on the cells called co -stimulators.

What type of non -phagocytic cell mediates inflammation?


A) basophil
B) neutrophil
C) eosinophil
D) natural killer (NK) cell

E) B) and C)
F) None of the above

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T cells directly interact with antigens without other cells involved.

A) True
B) False

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False

What cells decline in number during the final phase of HIV -1 infection, when an individual is said to have AIDS?


A) memory B cells
B) helper T (TH) cells
C) plasma cells
D) B cells

E) A) and B)
F) All of the above

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If the thymus shrank and stopped making hormones in a child, we would expect to see a decrease in the number of:


A) eosinophils.
B) T lymphocytes (T cells) .
C) neutrophils.
D) B lymphocytes (B cells) .

E) All of the above
F) B) and C)

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Cells that help regulate the immune response are:


A) cytotoxic T (TC) cells.
B) CD8 cells.
C) helper T (TH) cells.
D) major histocompatibility complex (MHC) molecules.

E) B) and C)
F) C) and D)

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Explain how a type I, or immediate, hypersensitivity is different from a typical primary immune response.

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Type I, or immediate, hypersensitivity r...

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Blood transfusions between incompatible blood types results in:


A) type II, or antibody -mediated, hypersensitivity.
B) type I, or immediate, hypersensitivity.
C) type III, or immune -complex mediated, hypersensitivity.
D) type IV, or delayed -type, hypersensitivity.

E) None of the above
F) All of the above

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Adaptive, or specific, immunity consists of antimicrobial proteins and certain cells that respond quickly to pathogens within the first 12 hours after exposure.

A) True
B) False

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Describe the functions of the lymphatic system.

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The lymphatic system has several functio...

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Lymph capillaries form a two -way system that moves lymph to and from the heart.

A) True
B) False

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False

Bill first had the influenza vaccine in October. He experienced a headache, achiness, fatigue, and a fever. When he came into contact with the influenza virus a few months later, he hardly had any symptoms at all. Explain these two different immune responses seen with each exposure to the virus.

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The primary immune response began with B...

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The clumping of cells that are cross -linked by their attachments to antibodies is known as:


A) agglutination.
B) precipitation.
C) neutralization.
D) opsonization.

E) A) and B)
F) None of the above

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Surface barriers, such as cutaneous and mucous membranes, serve the immune system as the:


A) third line of defense.
B) first line of defense.
C) second line of defense.
D) fourth line of defense.

E) B) and D)
F) All of the above

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IgM is the first antibody secreted by plasma cells when the body is invaded by a pathogen.

A) True
B) False

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Lymph traveling from the right arm will be filtered by:


A) inguinal lymph nodes.
B) cervical lymph nodes.
C) mesenteric lymph nodes.
D) axillary lymph nodes.

E) A) and D)
F) A) and C)

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