Question 1

Which of the following statements concerning plasma cells is TRUE?

Accepted Answer

A)   They can produce large quantities of antibodies on a daily basis.
B)   They are descended from activated T cells.
C)   They live for many years and function as memory cells.
D)   They secrete a variety of antibody molecules specific for multiple epitopes.
E)   The antibodies they produce can remain in circulation for years.F) A) and C)
G) B) and C)

Question 2

What is the result when a dendritic cell phagocytizes a microbe and processes it?

Accepted Answer

A)   suppression of the immune response to the microbe
B)   display of microbial fragments with CD8 glycoproteins
C)   display of epitope-MHC I complexes on the surface of the cell
D)   display of microbial epitope-MHC II complexes on the cell surface
E)   activation of the dendritic cell to become a plasma cellF) C) and D)
G) B) and E)

Question 3

Large molecules such as polymers make good antigens.

Accepted Answer

A) True 
 B)False

Question 4

IgG antibodies have a variety of mechanisms for acting on antigens.

Accepted Answer

A) True 
 B)False

Question 5

When a T cellʹs CD95L binds to the CD95 on a target cell, antibodies are formed.

Accepted Answer

A) True 
 B)False

Question 6

Adaptive immunity is sometimes also called acquired immunity. Which of the following statements provides a basis for the alternative name?

Accepted Answer

A)   To become activated, lymphocytes require exposure to the antigenic determinant for which they are specific.
B)   Lymphocytes of the adaptive immune system are highly specific for a single antigenic determinant.
C)   Activated lymphocytes produce daughter cells that are identical in specificity and function.
D)   Activated lymphocytes may persist for years in the body.
E)   Lymphocytes reactive to normal body components are removed.F) A) and D)
G) None of the above

Question 7

The role of dendrites in the adaptive immune response is to

Accepted Answer

A)   distinguish between endogenous and exogenous antigens.
B)   attack and destroy invading pathogens.
C)   process endogenous antigens for presentation on MHC I molecules.
D)   degrade exogenous antigens for presentation on MHC II molecules.
E)   detect autoreactive lymphocytes and trigger apoptosis.F) C) and D)
G) A) and B)

Question 8

When a T cell and an antigen-presenting cell interact, a specialized contact called an immunological (connection/bond/synapse) forms between them.

Accepted Answer

The answer of When a T cell and an antigen-presenting...

Question 9

A CD4+ T cell detects its epitope presented by an APC and receives IL-4 signals. It will differentiate to become a(n)

Accepted Answer

A)   CTL.
B)   APC.
C)   Th1 cell.
D)   Th2 cell.
E)   Tr lymphocyte.F) A) and B)
G) A) and D)

Question 10

IgE antibodies are best described as

Accepted Answer

A)   those involved in complement activation.
B)   the trigger for antibody-dependent cellular toxicity (ADC
C)  .
C)   the antibodies found in body secretions.
D)   a cause of basophil and eosinophil degranulation.
E)   the most common type of antibody in the blood during the initial phases of an immune response.F) B) and C)
G) A) and B)

Question 11

Clonal deletion of developing T lymphocytes takes place in which location(s)  in the body?

Accepted Answer

A)   the liver
B)   the spleen
C)   the thymus
D)   both the bone marrow and the spleen
E)   the bone marrowF) B) and E)
G) C) and E)

Question 12

Molecules with a molecular mass less than 5000 daltons can become antigens when they bind to carrier molecules.

Accepted Answer

A) True 
 B)False

Question 13

The antibody immune response is attributed to the action of

Accepted Answer

A)   macrophages.
B)   T lymphocytes.
C)   B lymphocytes.
D)   monocytes.
E)   neutrophils.F) A) and E)
G) A) and C)

Question 14

What types of antigens are bound to Class I MHC (major histocompatibility complex)  proteins?

Accepted Answer

A)   autoantigens
B)   both autoantigens and endogenous antigens
C)   exogenous antigens
D)   endogenous antigens
E)   autoantigens, endogenous, and exogenous antigensF) C) and D)
G) A) and B)

Question 15

Type 1 helper T (Th1)  cells produce to stimulate increased phagocytosis,

Accepted Answer

A)   gamma interferon (INF-γ) 
B)   growth factors
C)   chemokines
D)   alpha interferon (INF-α) 
E)   tumor necrosis factors (TNFs) F) A) and B)
G) None of the above

Question 16

B lymphocytes can bind directly to large antigens with repeating polysaccharide subunits, such as a bacterial capsule that has antigenic determinants known as T-independent (receptors/antigens).

Accepted Answer

The answer of B lymphocytes can bind directly to large...

Question 17

An antigen-presenting cell (APC) processes and displays (auto-/endogenous/exogenous) antigen.

Accepted Answer

The answer of An antigen-presenting cell (APC) processes and displays...

Question 18

Which of the following molecules would contain T-independent antigens?

Accepted Answer

A)   steroids
B)   phospholipids
C)   lipoproteins
D)   glycoproteins
E)   polysaccharidesF) A) and B)
G) A) and C)

Question 19

The perforin-granzyme pathway involves

Accepted Answer

A)   the production of antibodies toward the invading pathogen.
B)   binding CD95L to infected cells, which eventually leads to cell apoptosis.
C)   the production of fever, which kills the pathogen.
D)   the synthesis of special cell-killing proteins that act on infected or abnormal cells.
E)   presenting the foreign antigen to B cells.F) B) and D)
G) C) and E)

Question 20

The surface of each B lymphocyte is covered with about 250,000 to 500,000 identical copies of (BCR/MHC/TCR).

Accepted Answer

The answer of The surface of each B lymphocyte is...

Exam 16: Adaptive Immunity

A CD4+ T cell detects its epitope presented by an APC and receives IL-4 signals. It will differentiate to become a(n)

Correct AnswerverifiedShow Answer

IgG antibodies have a variety of mechanisms for acting on antigens.

Correct AnswerverifiedShow Answer

The antibody immune response is attributed to the action of

Correct AnswerverifiedShow Answer

The perforin-granzyme pathway involves

Correct AnswerverifiedShow Answer

IgE antibodies are best described as

Correct AnswerverifiedShow Answer

Type 1 helper T (Th1) cells produce to stimulate increased phagocytosis,

Correct AnswerverifiedShow Answer

Adaptive immunity is sometimes also called acquired immunity. Which of the following statements provides a basis for the alternative name?

Correct AnswerverifiedShow Answer

B lymphocytes can bind directly to large antigens with repeating polysaccharide subunits, such as a bacterial capsule that has antigenic determinants known as T-independent (receptors/antigens).

Correct AnswerverifiedShow Answer

When a T cell and an antigen-presenting cell interact, a specialized contact called an immunological (connection/bond/synapse) forms between them.

Correct AnswerverifiedShow Answer

An antigen-presenting cell (APC) processes and displays (auto-/endogenous/exogenous) antigen.

Correct AnswerverifiedShow Answer

What types of antigens are bound to Class I MHC (major histocompatibility complex) proteins?

Correct AnswerverifiedShow Answer

What is the result when a dendritic cell phagocytizes a microbe and processes it?

Correct AnswerverifiedShow Answer

The surface of each B lymphocyte is covered with about 250,000 to 500,000 identical copies of (BCR/MHC/TCR).

Correct AnswerverifiedShow Answer

Molecules with a molecular mass less than 5000 daltons can become antigens when they bind to carrier molecules.

Correct AnswerverifiedShow Answer

When a T cellʹs CD95L binds to the CD95 on a target cell, antibodies are formed.

Correct AnswerverifiedShow Answer

Which of the following molecules would contain T-independent antigens?

Correct AnswerverifiedShow Answer

Clonal deletion of developing T lymphocytes takes place in which location(s) in the body?

Correct AnswerverifiedShow Answer

The role of dendrites in the adaptive immune response is to

Correct AnswerverifiedShow Answer

Large molecules such as polymers make good antigens.

Correct AnswerverifiedShow Answer

Which of the following statements concerning plasma cells is TRUE?

Correct AnswerverifiedShow Answer

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