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The outcome of the joining of cytology and biochemistry yielded a better understanding of the cell by


A) identification of cellular structures.
B) identification of cellular biochemical pathways.
C) creating bioinformatics.
D) identification of cellular structures and biochemical pathways.
E) identification of biochemical pathways and creating bioinformatics.

F) C) and D)
G) C) and E)

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Glycolysis is also called the ________ pathway after the scientists who did most of the work to define it.

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________ is a biochemical technique that allows one to separate biological molecules based on size,shape,and/or affinity for specific molecules or functional groups.

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Wöhler revolutionized biology through his demonstration that biological molecules are governed by the ordinary laws of physics and chemistry.He demonstrated this principle by


A) synthesizing urea in the laboratory from ammonium cyanate.
B) developing techniques for isolating,purifying,and analyzing subcomponents of cells.
C) defining the laws of heredity.
D) discovering active agents in cell extracts that were specific biological catalysts that have since come to be called enzymes.
E) inventing mass spectrometry which is commonly used to determine the size and composition of individual proteins.

F) A) and D)
G) B) and C)

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You are studying the response of macrophages infected with the intracellular bacterium Brucella ,specifically by examining which gene products are being expressed.You would be studying the macrophage ________ to obtain this information.


A) proteome
B) genome
C) transciptome
D) amplicon
E) metabolome

F) B) and D)
G) A) and E)

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To which of the following do Mendel's observations relate?


A) thermodynamics
B) gravity
C) ideal gas laws
D) heredity
E) diffusion

F) A) and E)
G) B) and E)

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Gregor Mendel was most influential in which field of biology?


A) genetics
B) chromatography
C) biochemistry
D) prokaryotic transformation
E) cytology

F) None of the above
G) A) and D)

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Which of the following is an application of immunofluorescence microscopy?


A) Visualization of the natural fluorescence of a specimen under UV light.
B) Identification of specific components of the immune system.
C) Identifying which organelle or cellular compartment contains a particular protein.
D) Visualization of the surface structures of a specimen.
E) Construction of three-dimensional images of structures smaller than 10 nm.

F) C) and E)
G) A) and E)

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________ synthesized urea in the laboratory from inorganic starting materials.Much of what is now called ________ dates from this discovery.

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Friedrich ...

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Robert Hooke coined the term cell when studying thin slices of cork.These ________ were the first cells observed because ________.


A) dead plant cells; the thick cells walls did not require high resolution or magnification to view
B) dead animal cells; they were immobile and did not need to be fixed before viewing
C) compartments; they were actually the result of multiple cells that had merged and died to form large compartments that were easy to view
D) immune cells; they produce antibodies that embed in the cell membrane to make it visible
E) "little rooms"; they were 100 nm in diameter,much larger than most plant cells

F) C) and D)
G) A) and D)

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Melvin Calvin and his colleagues used which of the following to deduce the steps in the Calvin cycle?


A) negative staining
B) Drosophila melanogaster
C) electron microscopy
D) ultracentrifugation
E) radioisotopes

F) A) and B)
G) None of the above

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Once a scientific theory becomes a law,it


A) cannot be changed.
B) cannot be challenged.
C) becomes static.
D) is subject to modification.
E) is irrefutable.

F) D) and E)
G) C) and D)

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In 1880,Walther Flemming identified ________,threadlike bodies seen in dividing cells.

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Which of the following is mismatched?


A) Escherichia coli - genetics
B) Drosophila melanogaster - embryogenesis
C) Mus musculus - immunology
D) Caenorhabditis elegans - photosynthesis
E) Arabidopsis thaliana - plant gene function

F) B) and E)
G) D) and E)

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A number of different types of microscopy exist.Each type of microscopy has advantages and disadvantages.Can you identify the microscope that would be most advantageous for the situations below? a.A cell biologist wishes to visualize the ribosomes of a cell. b.A microbiologist wishes to examine the motility of a bacterium. c.An immunologist wishes to determine if a lymphocyte possesses a certain surface protein. d.A virologist is trying to determine the three-dimensional shape of a virus. e.A pathologist is trying to examine the cytoplasm of a cell for changes that result from viral infection.

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(Answers may vary.)
a.Electron microscop...

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A microtome is used to


A) view microscopic organisms.
B) slice thin sections of specimens.
C) focus short wavelengths of light.
D) manipulate tiny objects.
E) dissect cellular organelles.

F) A) and B)
G) A) and C)

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