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The inner layer of the glomerular capsule is composed of renocytes that have long cytoplasmic extensions.

A) True
B) False

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Explain the role of ANH (atrial natriuretic hormone) in homeostasis.

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ANH is secreted by the atria of the hear...

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Normally, concentrations of metabolically important substances, such as glucose, are


A) high in glomerular filtrate, but only found in trace amounts in urine.
B) low in glomerular filtrate, but high in urine.
C) high in both glomerular filtrate and urine.
D) low in both glomerular filtrate and urine.
E) excluded from entering the excretory system altogether.

F) B) and E)
G) C) and D)

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Jackie's ankles are very swollen at night after work. When she went to the doctor about the problem, the doctor requested a urine specimen. Why?


A) Jackie could be suffering from edema. If so, the urine sample might contain protein or urea.
B) Jackie is probably drinking too much water. If so, the urine will be very dilute.
C) Jackie might be suffering from kidney stones and the doctor is looking for small stones in the urine.
D) Jackie could have an inactive bladder and the doctor wants to see if Jackie is capable of urinating.

E) None of the above
F) A) and B)

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The cells of the distal convoluted tubules have numerous mitochondria to support active transport.

A) True
B) False

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"Artificial kidneys" do not function in all respects like a natural kidney. What is one inherent problem and what is its practical solution?


A) Artificial systems are less efficient; run the artificial kidney 24 hours a day.
B) Artificial kidneys are complex and must be operated at hospitals; train home care nurses.
C) Dialysis uses passive diffusion and some kidney functions require selective active transport; restrict diet to limit the variety of waste molecules.
D) Artificial kidneys treat the blood directly, requiring IV tubing, etc.; invent an alternative to avoid the bloodstream.
E) Blood coagulates any time it leaves the body; dilute the blood.

F) A) and E)
G) A) and D)

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Which step in urine formation occurs as molecules and ions are both passively and actively moved from the nephron into the blood of the peritubular capillary network?


A) glomerular filtration
B) tubular reabsorption
C) creatinine production
D) tubular secretion
E) filtration of small molecules into glomerular filtrate

F) C) and D)
G) C) and E)

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The bladder is expandable because it contains layers of elastic fibers embedded in thick layers of connective tissue.

A) True
B) False

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An antibiotic such as penicillin that is taken orally is soon excreted in the urine. Since infections last for a short period of time, what is the best strategy for overcoming this continual loss?


A) Provide another oral medication that stops cellular metabolism.
B) Provide a medication that prevents the filtration of all metabolites in the kidney.
C) Take a much larger single dose of penicillin.
D) Take continual doses of penicillin sufficient to maintain it in the bloodstream.
E) Provide a medication that prevents all reabsorption in the kidneys.

F) A) and D)
G) None of the above

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The wall of the ureter has three layers: an inner mucosa, a smooth muscle layer, and an outer fibrous coat of connective tissue.

A) True
B) False

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Nervous control of urination involves what mechanism(s) ?


A) The brain determines the need for urination from an internal clock.
B) Stretch receptors in the urinary bladder send impulses directly to the sphincters to cause urination.
C) Stretch receptors in the urinary bladder send impulses to the spine, causing a urinary reflex, but the brain can delay the reflex.
D) Stretch receptors in the urinary bladder directly send impulses to the brain that consciously decides to stimulate sphincters to relax.
E) Chemical receptors in the bladder detect urine concentration and trigger a reflex action.

F) None of the above
G) B) and E)

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The urethra serves what other body system in males?


A) endocrine
B) lymphatic
C) reproductive
D) digestive
E) immune

F) A) and B)
G) B) and D)

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Reabsorption of water, nutrients, and required salts occurs in what part of the nephron?


A) glomerulus
B) distal convoluted tubule
C) proximal convoluted tubule
D) collecting duct
E) loop of the nephron (loop of Henle)

F) C) and D)
G) A) and D)

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Which of the following would be an indication of kidney damage?


A) urea in the urine
B) salts in the urine
C) uric acid in the urine
D) large amount of protein in the urine
E) dilute urine

F) None of the above
G) All of the above

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Since the proximal convoluted tubule reabsorbs molecules by diffusion, what structure would you expect to find at the microscopic level?


A) microvilli to increase surface area
B) smooth muscle to stretch as the volume inside increases
C) numerous mitochondria to allow active transport
D) loose connective tissue so that liquids can pass through the cells
E) many neurons to stimulate the cells to reabsorb

F) A) and B)
G) A) and E)

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What capillaries are enclosed by the glomerular (Bowman's) capsule?


A) peritubular
B) glomerular
C) loop of nephron (loop of Henle)
D) collecting tubule
E) pulmonary

F) C) and E)
G) A) and E)

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The breakdown of amino acids in the liver releases


A) ammonia.
B) urea.
C) glucose.
D) creatinine.
E) uric acid.

F) A) and B)
G) A) and E)

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If the blood is alkaline


A) more hydrogen ions and bicarbonate ions are excreted.
B) less hydrogen ions and more bicarbonate ions are reabsorbed.
C) less hydrogen ions are excreted and less bicarbonate are reabsorbed.
D) the kidneys reabsorb increased amounts of water.
E) the diet must be low in necessary acids.

F) A) and B)
G) A) and E)

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What is the correct order an excreted water molecule moves from glomerulus to collecting duct?


A) loop of nephron → glomerular capsule → proximal convoluted tubule → distal convoluted tubule
B) glomerular capsule → proximal convoluted tubule → loop of nephron → distal convoluted tubule
C) glomerular capsule → proximal convoluted tubule → distal convoluted tubule → loop of nephron
D) proximal convoluted tubule → glomerular capsule → loop of nephron → distal convoluted tubule
E) distal convoluted tubule → glomerular capsule → proximal convoluted tubule → loop of nephron

F) A) and D)
G) B) and C)

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The buildup of the products of nucleic acid metabolism can lead to


A) gout.
B) creatinine.
C) erythropoietin.
D) renal failure.
E) urethritis.

F) B) and E)
G) A) and B)

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