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Which is most likely TRUE of an endocrine cell that contains an abundance of granular endoplasmic reticulum,a large Golgi apparatus,and secretion granules?


A) It secretes a peptide/protein hormone.
B) It secretes its product by diffusion through the lipid bilayer of the plasma membrane.
C) It secretes by endocytosis.
D) Its hormone product is synthesized from cholesterol.
E) It secretes a hormone with a hydrophobic structure.

F) A) and E)
G) B) and D)

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Which of the following statements about hormone actions is correct?


A) Growth hormone is a tropic hormone for insulin-like growth hormone.
B) Inhibition of prolactin release by dopamine is an example of short-loop negative feedback.
C) Somatostatin stimulates growth hormone secretion.
D) ACTH inhibits cortisol secretion.
E) Gonadotropic releasing hormone (GnRH) stimulates growth hormone secretion.

F) A) and B)
G) None of the above

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A deficiency in dietary iodine can cause:


A) congenital hypothyroidism (cretinism) .
B) a slowing of mental functions.
C) a low metabolic rate.
D) a goiter.
E) All of the choices are correct.

F) A) and B)
G) B) and E)

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Binding of hydrophilic hormones to their receptors often results in the formation of one or more second messengers that lead to alterations of the cell's activity.

A) True
B) False

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Which is NOT an effect of parathyroid hormone?


A) increases the bone degrading activity of osteoclasts
B) increases the bone building activities of osetoblasts
C) promotes vitamin D synthesis,leading to increased intestinal absorption of calcium
D) increases plasma [Ca2+]
E) decreases reabsorption of phosphate by the kidneys

F) C) and D)
G) B) and E)

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Which of the following is NOT stimulated by cortisol during stress?


A) gluconeogenesis
B) protein catabolism
C) glucose uptake into muscle cells
D) triglyceride catabolism in adipose cells
E) decreased sensitivity to insulin

F) B) and C)
G) A) and E)

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Which is NOT an endocrine function performed by the liver?


A) secreting insulin-like growth hormone
B) clearing hormones from plasma
C) secreting angiotensinogen
D) producing plasma proteins that bind hormones
E) secreting insulin

F) C) and D)
G) A) and B)

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Unlike neurons,endocrine cells generally do not act as integrators of various kinds of positive or negative inputs.

A) True
B) False

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Which of the following hormones is NOT usually secreted at higher levels in response to stress?


A) aldosterone
B) gonadotropins
C) vasopressin
D) antidiuretic hormone (ADH)
E) beta-endorphin

F) C) and D)
G) B) and E)

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What would be the effect of a thyroid deficiency beginning in infancy?


A) Gigantism would occur.
B) Laron dwarfism would occur.
C) Growth rate would be faster than normal.
D) Growth rate would be slower than normal.
E) Body temperature would be above normal.

F) B) and D)
G) B) and C)

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Short-loop negative feedback occurs when hormones from the ______________ inhibit hormone secretion by the ______________.


A) hypothalamus; anterior pituitary
B) adrenal cortex; hypothalamus
C) anterior pituitary; hypothalamus
D) adrenal cortex; anterior pituitary
E) anterior pituitary; adrenal cortex

F) B) and D)
G) A) and C)

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Thyroid hormones exert a permissive effect on the actions of epinephrine.

A) True
B) False

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Which of the following is true regarding pituitary growth hormone (GH) ?


A) The liver produces a factor that mediates the metabolic actions of GH.
B) GH stimulates insulin-like growth factor-1 (IGF-1) production by the liver and by many other cells.
C) GH increases the sensitivity of tissues to the action of insulin.
D) GH exerts negative feedback on its own production by inhibiting the hypothalamic secretion of somatostatin.
E) IGF-1 stimulates the secretion of GH by anterior pituitary gland cells.

F) B) and E)
G) A) and B)

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Which is a result of elevated thyroid hormone levels?


A) an increase in triglyceride storage
B) increased Na+/K+ ATPase activity
C) decreased body temperature
D) mental lethargy

E) C) and D)
F) A) and C)

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In cases where the plasma concentration of an ion or nutrient affects the secretion rate of a hormone,the affected hormone is usually a regulator of the homeostasis of that ion or nutrient.

A) True
B) False

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A precursor of cortisol is cholesterol.

A) True
B) False

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Which is an accurate description of the posterior pituitary and its functions?


A) It is glandular tissue,and secretes vasopressin and prolactin.
B) It is neural tissue,and is stimulated to secrete oxytocin and vasopressin by hypophysiotropic hormones.
C) It is neural tissue,and vesicles containing oxytocin and vasopressin are transported to axon terminals there.
D) It is glandular tissue,and releases oxytocin and somatostatin when action potentials arrive along axons from the hypothalamus.
E) It is neural tissue that secretes hypophysiotropic hormones that control the secretion of the anterior pituitary hormones.

F) B) and D)
G) None of the above

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Which is a function of the gonadotropic hormones?


A) stimulating the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH)
B) inhibiting the release of growth hormone
C) inhibiting the release of prolactin
D) inducing the secretion of steroid hormones by the gonads in both males and females
E) stimulating the release of gonadotropin-releasing hormone (GnRH)

F) B) and C)
G) A) and E)

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In general,the metabolism and excretion rates of steroid hormones are higher than those of peptide hormones.

A) True
B) False

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Which of the following statements about oxytocin is TRUE?


A) Target cells of oxytocin have receptors for the hormone in their nuclues.
B) Oxytocin is synthesized in the hypothalamus.
C) Oxytocin is secreted by the anterior pituitary gland.
D) Oxytocin's main function is to increase the rate of respiration.
E) Oxytocin keep uterine smooth muscle from contracting,so it prolongs pregnancy.

F) A) and E)
G) C) and D)

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